• Hitting an Invisible Target in TB Vaccine Design

    I have a troubled relationship with Twitter. It’s an unredeemable hate sort of thing. I’m generally an inane mix of angry opinion and low self-esteem so, in theory, we’re perfect for each other. I just don’t feel it, though. I had a quick look for online videos in the same vein of the YouTube...
  • Dark Matter: What’s Science Got to Hide?

    Scientific data is more freely available than ever. But does the push for openness help or hinder science? A panel debate at Imperial College London on 6th December sought to answer this question, launching the latest edition of Index on Censorship magazine—a special issue focussing on...
  • Rebranding Tuberculosis

    If infectious diseases were monsters, what would they look like? I imagine malaria would be a terrible mosquito-like creature made of bones, with a wickedly sharp proboscis and a throbbing gut of fiery red blood. Diarrhoeal disease would rise from a swamp of sewage, grinning with its skull’s jaw...
  • Lag phase adapts bacteria to new environments

    Forgotten to defrost the chicken overnight in the fridge? That’s fine—you can leave it to thaw at room temperature, right? It will be quicker, after all… But, within just a few hours, the tiny bacteria hiding in frozen food such as chicken, beef or that left over Chinese takeaway can start to...
  • Middle of the Road Pays for Pathogens

    To understand why infectious diseases make us ill, it helps to consider disease from the pathogen’s point of view. Bacteria, viruses and parasites did not evolve simply to cause illness and suffering; virulence is simply a by-product of a pathogen’s fight for survival. Because an infectious...
  • Faecal Transplants Through the Medium of Cartoons

    Faecal transplants are highly effective in treating recurrent Clostridium difficile infections compared to conventional antibiotics. The transplants proved so successful that the trial was stopped early to give other patients the chance to benefit from this slightly icky-sounding treatment,...

Friday, 27 January 2012

What's all the fuss about? Flu isn't so bad, right? Seasonal flu is an annoyance for most people but, in the young or elderly, or immunocompromised individuals, it can still be fatal. Each year, there are around 4,000 deaths attributed to flu in the UK, despite these people having access to health care and anti-viral medicines. So...

Saturday, 21 January 2012

Forgotten to defrost the chicken overnight in the fridge? That’s fine—you can leave it to thaw at room temperature, right? It will be quicker, after all… But, within just a few hours, the tiny bacteria hiding in frozen food such as chicken, beef or that left over Chinese takeaway can start to divide. Fail to cook the meal...

Sunday, 15 January 2012

A Salmonella infection has some very obvious and unpleasant effects on the unfortunate person who failed to wash or cook their food correctly. But it also messes with the bacteria that live in our guts, and that’s not a good thing when it comes to the emergence of new pathogens that can make us extremely sick....

Tuesday, 10 January 2012

What does an Egyptian mummy have in common with one-third of the world’s population? The answer is tuberculosis (TB)—a disease which has been affecting mankind since prehistoric times. But, I hear you muttering, didn’t we already cure TB? Um, not really. Around 1.7 million people die from TB every year and the HIV epidemic is only...

Saturday, 7 January 2012

Researchers at UC San Diego have created living 'neon signs' from glowing bacteria which flash on and off in unison. As described in this week's Nature, the researchers used this technology to create a bacterial sensor for detecting low levels of arsenic. I like to imagine that the scientists working in Jeff Hasty’s lab at...