• Stealth Tactics of the Black Death Bacterium

    Yersinia pestis holds the dubious title of the world's most devastating bacterial pathogen. While its glory days of the Black Death are thankfully a thing of the past, this pathogen remains a threat to human health to this day. A recent paper published in PNAS describes how the...
  • Hitting an Invisible Target in TB Vaccine Design

    I have a troubled relationship with Twitter. It’s an unredeemable hate sort of thing. I’m generally an inane mix of angry opinion and low self-esteem so, in theory, we’re perfect for each other. I just don’t feel it, though. I had a quick look for online videos in the same vein of the YouTube...
  • Susceptibility to Tuberculosis

    What does an Egyptian mummy have in common with one-third of the world’s population? The answer is tuberculosis (TB)—a disease which has been affecting mankind since prehistoric times. But, I hear you muttering, didn’t we already cure TB? Um, not really. Around 1.7 million people die from TB every...
  • When Bad Bugs Go Badder

    The Beijing lineage of M. tuberculosis is the villain in a movie sequel. Nastier, scarier, harder to kill. You thought tuberculosis (TB) was bad? Think again. The Beijing lineage is that little bit worse, associated with a speedier disease progression and increased antibiotic resistance. I’ve...
  • Dark Matter: What’s Science Got to Hide?

    Scientific data is more freely available than ever. But does the push for openness help or hinder science? A panel debate at Imperial College London on 6th December sought to answer this question, launching the latest edition of Index on Censorship magazine—a special issue focussing on...
  • Not born this way, or why I think Lady Gaga is underselling the awesomeness of the human race

    There’s a lot in the news at the moment about a little boy who has been diagnosed with Gender Identity Disorder and is now living as a girl. I can’t quite decide how I feel about this. Part of me thinks it is awesome that his parents and teachers are being so supportive—god knows we could do...

Friday, 26 October 2012

I recently finished a month-long British Science Association Media Fellowship, spending three weeks at Nature and one week at the British Science Festival in Aberdeen. I’ve talked more about my thoughts on this experience at the Wellcome Trust blog. I’m now left wondering what on Earth I am going to do with all my newfound skillz....

Saturday, 22 September 2012

Kate Middleton’s boobs are everywhere, both in the flesh and spirit. That sounds like the plot of a horror film in itself (“Nooooo, we’re surrounded, I’m suffocating!”). But what I really want to bring to your attention is how boobs are somehow capable of turning normal, rational people into adipose-for-brains morons. Not coming...

Sunday, 26 August 2012

I made the worst decision of my life the other day and think the guilt will linger for at least another decade. You know those little parks you can go to which are liberally scattered with ducks? Ducks on all the ponds, ducks mingling with the sheep and random alpacas, ducks pestering visitors for food in the picnic areas?...

Tuesday, 21 August 2012

  A 500-word news article on a research paper and two days to write it. You'd think it would be simple. Yeah, right. One week into my first foray into the world of science journalism and I feel like my soul has been severely paper-cut with my own poorly phrased copy. To be fair, the majority of the responsibility for...

Saturday, 18 August 2012

I’m a week into a month-long placement in a science journalism office made up of real journalists and me – a research scientist who is rapidly learning a new respect for those who write about science in a professional capacity. In the past, I know I’ve Googled ‘where do science journalists get their ideas’ and ‘how to write about...

Wednesday, 15 August 2012

For the next month, I am taking a teeny break from science to pretend to be a journalist at Nature News. It's a scheme aimed at teaching working scientists about how the media works by dragging them out of the lab, bleary eyed with the residual smell of growth media lingering upon their person, into the wonderful world of 10am...

Sunday, 1 July 2012

Finishing Things

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So last week I ‘finished’ my latest book. It’s a young adult novel about a girl who can find lost things and the search for a mythical forgotten city with a beating stone heart said to hold the key to immortality. Also, man-eating gargoyles. I’m not very good at finishing things, so getting to the point when I can bear to...

Sunday, 27 May 2012

It makes me laugh when I hear people say that they don’t like fantasy or science fiction novels because ‘it’s not real’. All fiction, by definition, is made up. Yet, when it comes to imaginary monsters or aliens or magicians with pointy hats and white beards, many people don’t want to read something so removed from reality....

Saturday, 14 April 2012

African sleeping sickness is one of those scary diseases that seems kind of alien to anyone living in the Western world but which is a real threat to those living in sub-Sahara Africa, causing around 50,000 cases each year. The disease gets its name from the most recognisable symptom—a disruption of sleeping patterns after the parasite...

Tuesday, 3 April 2012

At this time of year, the Kruger National Park in South Africa reaches temperatures of up to 38 degrees Celsius. This has nothing to do with the subject of this post, but I thought I would use it to illustrate one of my newly recognised great discoveries of the 20th century—in-car air-conditioning. It’s a pretty tenuous link to...

Sunday, 26 February 2012

Yersinia pestis holds the dubious title of the world's most devastating bacterial pathogen. While its glory days of the Black Death are thankfully a thing of the past, this pathogen remains a threat to human health to this day. A recent paper published in PNAS describes how the bacterium switches off the immune system...

Tuesday, 21 February 2012

There’s a lot in the news at the moment about a little boy who has been diagnosed with Gender Identity Disorder and is now living as a girl. I can’t quite decide how I feel about this. Part of me thinks it is awesome that his parents and teachers are being so supportive—god knows we could do with a bit more understanding when...

Monday, 20 February 2012

I have a slight obsession with the sewers, which I don’t think is entirely normal or healthy. It’s the architecture more than the sewage itself but, as it happens, this post concerns the latter. Our tour of interesting things poo-related starts in London of 1858 and a period of history known as the Great Stink. The first half...

Friday, 17 February 2012

I went to a birthday gathering in a pub the other day to which someone had brought along the game Jenga. Putting aside any conclusions you may want to make as to just how exciting it must be to party with my friends and me, the game actually illustrates an interesting point about evolution. Sort of.  The idea of Jenga is...

Sunday, 12 February 2012

Like animals, plants can be infected by a range of pathogenic organisms. And, like animals, plants possess an immune system to fight off attacks from pathogens. The plant immune system is analogous to the innate immune system in higher eukaryotes but does not involve mobile immune cells such as macrophages. Instead,...

Wednesday, 1 February 2012

To understand why infectious diseases make us ill, it helps to consider disease from the pathogen’s point of view. Bacteria, viruses and parasites did not evolve simply to cause illness and suffering; virulence is simply a by-product of a pathogen’s fight for survival. Because an infectious agent which incapacitates its host...